Abstract
This article presents a substantially revised academic version of the author-provided manuscript devoted to the biochemical effects of combined chitosan and whey powder administration on glucose homeostasis and insulin sensitivity. The manuscript was restructured according to the standard scientific article format, and terminological, stylistic, and logical inconsistencies of the source text were corrected. The analysis indicates that chitosan can attenuate intestinal absorption of carbohydrates and lipids, modulate the gut microbiota, and reduce postprandial glycemic excursions, whereas whey protein enhances incretin release, stimulates insulin secretion, and improves GLUT-4-mediated glucose utilization in peripheral tissues. When used together, these components may support AMPK- and PI3K/Akt-related regulatory pathways, decrease metabolic inflammation, and improve overall substrate handling. Therefore, the combination may be regarded as a promising nutritional-biochemical strategy for metabolic syndrome, obesity, and states associated with impaired insulin sensitivity.
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