Abstract
Laryngopharyngeal reflux (LPR) is a common but often underdiagnosed condition in otorhinolaryngology characterized by the backflow of gastric contents into the larynx and pharynx, leading to chronic irritation of the upper airway mucosa. Unlike gastroesophageal reflux disease (GERD), LPR typically occurs without heartburn and primarily manifests with extraesophageal symptoms such as hoarseness, chronic throat clearing, cough, globus sensation, and postnasal drip. The condition affects a significant portion of patients seen in ENT clinics and has been associated with laryngeal inflammation, vocal fold lesions, and chronic rhinosinusitis. Due to its nonspecific presentation and overlap with other laryngeal and respiratory disorders, LPR poses diagnostic and therapeutic challenges. Advances in diagnostic modalities, including pH impedance monitoring and flexible laryngoscopy, have improved clinical recognition, while novel treatment strategies combining medical therapy, lifestyle modification, and dietary interventions have enhanced patient outcomes.
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