RATIONAL USE OF ANTIBIOTICS IN HOSPITAL SETTINGS: STRATEGIES TO REDUCE ANTIMICROBIAL RESISTANCE

Abstract

strengthening stewardship programs, improving clinical decision-making, and implementing evidence-based protocols significantly improve patient safety and preserve the long-term effectiveness of antibiotics. The increasing prevalence of antimicrobial resistance in hospital settings presents a critical challenge to effective infectious disease management and patient safety. This study explores comprehensive strategies aimed at promoting the rational utilization of antibiotics within healthcare facilities. It focuses on the implementation of antibiotic stewardship programs, diagnostic optimization, and prescriber education as pivotal tools to curb inappropriate prescribing and minimize resistance development. By analyzing institutional antibiotic consumption, prescribing behaviors, and infection control practices, the research underscores the necessity for coordinated interventions that balance therapeutic efficacy with resistance mitigation. The results demonstrate measurable improvements in antibiotic use patterns, reduction in broad-spectrum agent overuse, and a decline in multidrug-resistant infections, reinforcing the importance of systemic stewardship frameworks to safeguard antimicrobial efficacy.