RATIONAL USE OF ANTIBIOTICS IN HOSPITAL SETTINGS: STRATEGIES TO REDUCE ANTIMICROBIAL RESISTANCE

Abstract

Annotation: This study analyzes key principles and institutional strategies that
support the appropriate use of antibiotics in hospital environments to reduce the spread
of antimicrobial resistance. By evaluating prescribing patterns, diagnostic accuracy,
stewardship interventions, and monitoring systems, the research highlights practical
tools that optimize therapeutic outcomes, minimize unnecessary exposure to
antimicrobial agents, and prevent the emergence of resistant pathogens. The findings
demonstrate that strengthening stewardship programs, improving clinical decision
making, and implementing evidence-based protocols significantly improve patient
safety and preserve the long-term effectiveness of antibiotics. The increasing
prevalence of antimicrobial resistance in hospital settings presents a critical challenge
to effective infectious disease management and patient safety. This study explores
comprehensive strategies aimed at promoting the rational utilization of antibiotics
within healthcare facilities. It focuses on the implementation of antibiotic stewardship
programs, diagnostic optimization, and prescriber education as pivotal tools to curb
inappropriate prescribing and minimize resistance development. By analyzing
institutional antibiotic consumption, prescribing behaviors, and infection control
practices, the research underscores the necessity for coordinated interventions that
balance therapeutic efficacy with resistance mitigation. The results demonstrate
measurable improvements in antibiotic use patterns, reduction in broad-spectrum
agent overuse, and a decline in multidrug-resistant infections, reinforcing the
importance of systemic stewardship frameworks to safeguard antimicrobial efficacy.